Claudio Brovida - Research thesis
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Thesis published in Italian
Translated by Google translate |
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Abstract
Renal dysplasia is defined as a disorganized development of the renal parenchyma, consequent to an anomalous differentiation of the nephron’s various segments. The final diagnosis is based on the correct histopathology evaluation of the kidney and the finding of the typical structural anomalies. In Boxer dogs, renal dysplasia, also defined juvenile nephropathy, has been described, however the published material on this topics is still limited and different theories about the development of this disease are proposed. The author, starting from the evaluation of a group of cases of juvenile nephropathy, that he diagnosed, by kidney biopsy, in a period of five years, planned a prospective study, on a population of young Boxers, aging a mean of 12 months, which have been evaluated during one year of time. Starting from a group of 120 investigated Boxers, he included in the study 84 dogs on which basic haematology, biochemistry and urinalysis tests have been performed. The consequent data, statistically evaluated, have been analysed to envisage elements that could help to define an early detection of signs of renal damage, that may be associated to a juvenile nephropathy, in these Boxer dogs.
Renal dysplasia is defined as a disorganized development of the renal parenchyma, consequent to an anomalous differentiation of the nephron’s various segments. The final diagnosis is based on the correct histopathology evaluation of the kidney and the finding of the typical structural anomalies. In Boxer dogs, renal dysplasia, also defined juvenile nephropathy, has been described, however the published material on this topics is still limited and different theories about the development of this disease are proposed. The author, starting from the evaluation of a group of cases of juvenile nephropathy, that he diagnosed, by kidney biopsy, in a period of five years, planned a prospective study, on a population of young Boxers, aging a mean of 12 months, which have been evaluated during one year of time. Starting from a group of 120 investigated Boxers, he included in the study 84 dogs on which basic haematology, biochemistry and urinalysis tests have been performed. The consequent data, statistically evaluated, have been analysed to envisage elements that could help to define an early detection of signs of renal damage, that may be associated to a juvenile nephropathy, in these Boxer dogs.
