Measuring Glomerular Filtration Rate (GFR)
This is the most sensitive test we have at present for evaluating renal function, and it can detect loss of renal function at an early stage. The test measures the rate at which the kidneys filter a substance from the bloodstream. A decreased GFR is a sign of kidney disease, and it can be used to evaluate both the severity and progression of kidney disease. The test is performed by administering a substance such as creatinine or iohexol into the bloodstream through a catheter followed by repeated collections of blood samples to measure the time it takes until the substance has been cleared from the bloodstream. This test will be a sensitive tool to screen for Boxer JKD.